P-5: Assessment of Sperm Chromatin Status in Rat Experimental Varicocele

Increased Sperm DNA Damage in Experimental Rat Varicocele Model and The Beneficial Effect of Varicocelectomy

P-13: Evaluation of Sperm Acrosin Activity and Chromatin Structure in Varicocele Patients Before and after Varicocelectomy

Background: Evaluation and comparison of total acrosin activity along with DNA integrity in the semen samples obtained from the varicocele individuals before and after the surgery and also in fertile individuals. Materials and Methods: Semen parameters, protamine deficiency, DNA fragmentation and Total acrosin activity were measured in patients with a clinical diagnosed varicocele of grade II o...

P-59: Effect of Microsurgical Varicocelectomy on Sperm Chromatin Packaging,Miscarriage and Pregnancy Rate in Infertile Men with Varicocele

Background: Although the pathophysiology of the testicular damage associated with varicocele remains unclear, but varicocelectomy is considered a suitable technique for the treatment of individuals with clinical varicocele. The current study was designed to assessed semen parameters, chromatin packaging, and pregnancy outcome before and after varicocelectomy. Materials and Methods: Semen sample...

P-11: Varicocele Improved Semen Quality and Chromatin Integrity in Normozoospermic and Non-Normozoospermic Varicocele Individual

Background: Varicocele is related with poor semen quality and sperm chromatin integrity which possibility decreases the spontaneous pregnancy potential. Some of the varicocele individuals have normal semen parameters with failed pregnancy. It is also one of the most controversial issues in the field ofinfertility, especially regarding why, when and for whom varicocelectomy should be implemented...

O-4: Protective Effect of Silymarin on Sperm Viability and Chromatin Packing in Varicocele-Induced Rats

Background: Varicocele has been repeatedly implicated as a cause of infertility in selected men. Previous studies have showed high levels of seminal oxidative stress, as evidenced by increased levels of ROS and reduced total antioxidant capacity in varicocele men, suggesting that sperm dysfunction in varicocele patients may be partly related to oxidative stress. Thus current study was designed ...

Increased Sperm DNA Damage in Experimental Rat Varicocele Model and The Beneficial Effect of Varicocelectomy

BACKGROUND Varicocele, the abnormal dilatation of the veins in the pampiniform plexus is commonly seen in infertile patients. In this study, we aim to examine sperm DNA damage after the creation of experimental varicocele in rats and to observe the change of this damage after a varicocelectomy. MATERIALS AND METHODS In this experimental study, a total of 30 adult male Wistar albino rats were ...